Effects of Type Two Diabetes Mellitus on Lung Function Parameters

Diabetic patients may have significant reduction in lung functions as chronic hyperglycemia in Type two Diabetes Mellitus (T2 DM) is associated with continuing damage, dysfunction, and failure of various organs, especially the eyes, kidneys, nerves, heart, lungs and blood vessels. This study was carried out on One hundred T2 DM patients, age between 30-70 years of either gender who were subjected to Spirometry, their vital parameters were recorded, glycated hemoglobin (HbA1c) and fasting blood sugar (FBS) were analyzed and matched with healthy controls.Forced Vital Capacity (FVC) in diabetics ranged from 1.52 – 4 (Liters) mean 2.5 ± 0.7SD whereas in controls it ranged from 2.3 4.75 mean 3.15 ± 0.6SD with significant P value. (P < 0.001) Peak Expiratory Flow Rate (PEFR) in diabetics ranged from 189 – 460 (Liters per minute) mean 289 ±71SD whereas in controls it ranged from 244 – 572 mean 374 ±75 with significant P value. (P < 0.001) PEFR in female diabetics was 240 ± 39SD with significant P value when compared to male diabetics. (P < 0.001) In male diabetics spirometric indices were found insignificant as compared to healthy controls. (P > 0.05) HbA1c and FBS were found highly significant in patients when compared with controls in both sexes. (P < 0.001) Combined comparison of both sexes showed impaired FVC and PEFR. Lung function variable PEFR was seen impaired in Female Diabetics while male diabetics showed normal PEFR as compared to healthy controls.